Gastrointestinal: Collagenous Sprue
نویسندگان
چکیده
منابع مشابه
Concomitant presentation of collagenous sprue and HFE hemochromatosis.
Collagenous sprue (CS) is a progressive malabsorptive disorder characterized by collagen deposition beneath the basement membrane of small bowel epithelium in refractory celiac sprue. CS is a pathologically distinct entity from celiac disease, despite a similar clinical presentation. The etiology of CS is unclear, although there are speculations that CS and celiac disease may share similar path...
متن کاملThe first cases of collagenous sprue successfully treated with thioguanine
OBJECTIVE Collagenous sprue (CS) is a rare form of small bowel enteropathy characterised by a thickened basement membrane and is, in most of the literature, reported as part of coeliac disease. Multiple treatment strategies are suggested in CS, but there is no standardised therapy. The aim of this series is to describe 4 cases of CS and to propose thioguanine (6-TG) treatment. DESIGN We revie...
متن کاملSuccessful treatment of collagenous sprue with combination of prednisolone and gluten-free diet.
A case is described of adult coeliac disease with subepithelial collagen in a jejunal biopsy ('collagenous sprue') which responded well to treatment with prednisolone in addition to a gluten-free diet. The indications for corticosteroid treatment in adult coeliac disease are discussed in the light of the findings. It is suggested that collagenous sprue may represent the most severe form of adul...
متن کاملRefractory coeliac sprue is a diffuse gastrointestinal disease.
BACKGROUND Refractory coeliac sprue (RCS) with an immunophenotypically aberrant clonal intraepithelial lymphocyte (IEL) population is considered a cryptic form of intestinal T cell lymphoma. AIMS To investigate the distribution of the abnormal and monoclonal IEL population in the digestive tract of RCS patients. PATIENTS AND METHODS We compared the frequency of lymphocytic gastritis (LG) an...
متن کاملCOELIAC DISEASE Refractory coeliac sprue is a diffuse gastrointestinal disease
Background: Refractory coeliac sprue (RCS) with an immunophenotypically aberrant clonal intraepithelial lymphocyte (IEL) population is considered a cryptic form of intestinal T cell lymphoma. Aims: To investigate the distribution of the abnormal and monoclonal IEL population in the digestive tract of RCS patients. Patients and methods: We compared the frequency of lymphocytic gastritis (LG) and...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2010
ISSN: 0815-9319
DOI: 10.1111/j.1440-1746.2010.06471.x